A 38-year-old female presents to the emergency room with fever, skin purpura, and sudden onset of weakness in her right arm. The patient reports that she developed a low-grade fever and noticeable purpura on her legs and arms three days ago, which have progressively worsened. Early this morning, she experienced sudden weakness in her right arm, prompting her to seek immediate medical attention.
What is the most appropriate next step?
Labs reveal hemolytic anemia (high LDH and unconjugated hyperbilirubinemia), thromboyctopenia and high levels of creatinine. What is the next diagnostic work up to prove TTP?
Which of the following points towards the diagnosis of TTP rather than HUS?
EKG shows sinus rhythm, 80 bpm, no axis deviation. What is the purpose of doing an EKG to this patient?
Head CT is done to evaluate the neurological symptoms. In TTP, what kind of findings do you expect on the CT?
What is the management of the TTP?
What is the mechanism of action of rituximab?
